A photon-counting detector for dual-energy breast tomosynthesis

What is early enough in any individual case is uncertain because there are insufficient outcomes data.


True extent of the lesion was made out in Large reader variations occurred with each modality. Of the MRI participants, 16 women 2. Published studies of DBT were relatively small studies, mostly test-set observer reader studies or clinical series that included symptomatic and screen-recalled cases, and were generally enriched with cancers.

The reconstructed tomosynthesis slices can be displayed similarly to computed tomography reconstructed slices. A total of 2, women, with at least heterogeneously dense breast tissue in at least 1 quadrant, were recruited from 21 sites to undergo mammographic and physician-performed ultrasonographic examinations in randomized order by a radiologist masked to the other examination results.

They included studies on diagnostic tests and systematic reviews. They stated that use of DBT may reduce recall rates; effects of supplemental screening on breast cancer outcomes remain unclear.

A total of 78, screening mammograms from October 11,to June 30,were retrospectively collected.

Photon Counting Energy Dispersive Detector Arrays for X-ray Imaging

The experimental results were compared against the values obtained from a theoretical model of the imaging system.

Gilbert et al stated that digital breast tomosynthesis DBT is a 3D mammography technique with the potential to improve accuracy by improving differentiation between malignant and non-malignant lesions.

To mitigate motion artifacts, a detector composed of 2 layers may be used to simultaneously acquire the low and high energy images. Breast cancer status was determined for 42, women, the group included in this study. Radiologists' accuracy was also calculated.

The quantities of enhancement were informative for assessing breast lesions in which the malignancies had stronger enhancement and more relative depressed enhancement than the benign lesions. A total of 49 participants who underwent both CESM and CEMRI, as part of a larger trial, completed a Likert questionnaire about their preference for each modality according to the following criteria: One method moves the detector in concert with the x-ray tube so as to maintain the shadow of the breast on the detector.

If these results were observed with screening cases, DBT and 2D mammography could benefit to the screening program by reducing the number of women recalled unnecessarily, especially if a synthetic 2D mammogram were used to minimize radiation exposure.

They then compared the performance of the 2 detectors under the variation of contrast agent concentration, tumor size and dose. English-language systematic reviews, randomized trials, and observational studies of screening were selected for analysis.

This is typically done via a process of "windowing", which maps a range the "window" of pixel values to a grayscale ramp.

The authors concluded that the Adjunct Screening With Tomosynthesis or Ultrasound in Women With Mammography-Negative Dense Breasts' interim analysis showed that ultrasound has better incremental BC detection than tomosynthesis in mammography-negative dense breasts at a similar FP-recall rate.

In order to improve contrast at reduced dose, photon-counting detectors have been considered to develop alternatives to conventional X-ray detectors used in radiography and CT [ 1 ]—[ 3 ].

CAD is not intended to be used in place of a radiologist but as a second set of eyes when examining the images. This study had several drawbacks.

These researchers examined supplemental cancer detection yield of ultrasound and MRI in women at elevated risk for breast cancer. There are 2 basic tomosynthesis system designs that differ in the motion of the detector during acquisition.

As previously described, 4 we propose a system design where LE and HE images are acquired in a single scan in which alternate slits of the multislit prepatient collimator are covered with Sn and Cu.

Eligible women had tomosynthesis and physician-performed ultrasound with independent interpretation of adjunct imaging.

Also, detectors with multiple layers may be more expensive to produce. The authors concluded that the use of contrast-enhanced tomographic mammography has been demonstrated successfully in patients with promising diagnostic benefit.

A screening mammography is one of several tools that are used for early detection of breast cancer in asymptomatic women. The change in the cancer-detection rate including invasive breast cancers and ductal carcinomas in situ was insignificant 4. Artifacts are caused by abrupt transitions between low- and high-density materials, which results in data values that exceed the dynamic range of the processing electronics.

This approach has a number of disadvantages related to the interconnections between the various layers and readout electronics. A total of 3 radiologists analyzed 8 CESM and FFDM measurements separately, considering the size of the residual tumor at its largest diameter and correlating it with that determined in the pathological analysis; inter-observer agreement was also evaluated.

The detectability was found to be most comparable at the lower end of the evaluated factors. Incremental FP recall occurred in participants 3. Objects at different heights in the breast project differently for each angle. A data set of 2-view DBT of 72 breasts containing micro-calcification clusters was collected from 72 subjects who were scheduled to undergo breast biopsy.Purpose: Previously, the authors developed a dual-energy (DE) acquisition technique for a photon-counting digital breast tomosynthesis (DBT) imaging system.

Low-energy (LE) and high-energy (HE) images are acquired in a single scan by covering alternate slits of a multislit prepatient collimator with. The raw data sets are processed with a dual energy calibration technique that enables projection space reconstruction and eliminates the beam hardening effect.

Olla H, Penton E, Rantanen J, Solokov S, Weber N, Westerberg H. Evaluation of a photon-counting breast tomosynthesis imaging system. Med ImagProc SPIE. First.

Background. A mammogram is an x-ray of the breast. A screening mammography is one of several tools that are used for early detection of breast cancer in asymptomatic women. A multislit photon-counting tomosynthesis system was utilized (spectral imaging) to produce both low- and high-energy tomographic data (below and above the k edge of iodine, respectively) in a single scan, which allowed for dual-energy visualization of iodine.

CT scan can be used for detecting both acute and chronic changes in the lung parenchyma, that is, the internals of the lungs. It is particularly relevant here because normal two-dimensional X. Learn how individuals, institutions and agencies can access our journals.

A photon-counting detector for dual-energy breast tomosynthesis
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